TITLE: GCN CIRCULAR NUMBER: 40103 SUBJECT: IceCube-250406A - IceCube observation of a high-energy neutrino candidate track-like event DATE: 25/04/07 08:06:32 GMT FROM: A. Zegarelli at Ruhr University Bochum The IceCube Collaboration (http://icecube.wisc.edu/) reports: On 2025-04-06 at 22:50:35.34 UT IceCube detected a track-like event with a high probability of being of astrophysical origin. The event was selected by the ICECUBE_Astrotrack_GOLD alert stream. The average astrophysical neutrino purity for bronze alerts is 50%. This alert has an estimated false alarm rate of 0.9358 events per year due to atmospheric backgrounds. The IceCube detector was in a normal operating state at the time of detection. After the initial automated alert (https://gcn.gsfc.nasa.gov/notices_amon_g_b/140752_31006975.amon), more sophisticated reconstruction algorithms have been applied offline, with the direction refined to: Date: 2025-04-06 Time: 22:50:35.34 UT RA: 81.47 (+0.54, -0.53 deg 90% PSF containment) J2000 Dec: 16.96 (+0.42, -0.50 deg 90% PSF containment) J2000 No gamma-ray sources from 4FGL or 3FHL catalogs are in the 90% uncertainty region. We encourage further follow-up by ground and space-based instruments to help identify a possible astrophysical source for the candidate neutrino. The IceCube Neutrino Observatory is a cubic-kilometer neutrino detector operating at the geographic South Pole, Antarctica. The IceCube realtime alert point of contact can be reached at roc@icecube.wisc.edu